Get Adobe Flash player

harvard epidemiology professor

Professor of Public Health and Epidemiology. Modeling work (with Caroline Buckee) focuses on studies of the population-biologic effects of such immune responses. Ed Goldstein, who led most of this work, is currently extending it to other outcomes including hospitalization. Associate Professor of Epidemiology, Harvard T.H. Currently we are working with several groups to model the impact of pneumococcal vaccine programs. Psychiatric epidemiology... Read more about Alan M. Zaslavsky. With Laura White and collaborators at CDC we made an early estimate of the pandemic reproductive number from CDC line list data. Associate Professor of Epidemiology. We undertook several analyses of severity, first in Mexico, and later in the US and UK (with Anne Presanis and multiple collaborators in public health agencies). Kolokotrones Professor of Biostatistics and Epidemiology Departments of Epidemiology and Biostatistics. Bill Hanage, an associate professor of epidemiology at the Harvard T.H. CNN anchor Brianna Keilar … In an article entitled You’re Likely to Get the Coronavirus , the Atlantic explains how the coronavirus is particularly dangerous because it may cause cause no symptoms at all in many carriers of the infection. He also directs the Center for Communicable Disease Dynamics, a center of excellence funded by the MIDAS program of NIH/NIGMS, and the … Chan School of Public Health, Choosing a Program to Study Infectious Diseases at Harvard T.H. Much of this work has been led by Daniel Weinberger, first while he was in our group and recently while he is on the faculty at Yale. Jose Zubizarreta. My research concerns the effect of naturally acquired host immunity, vaccine-induced immunity and other public health interventions (e.g. Want to keep up-to-date on the latest department news? This has developed into systematic efforts at influenza forecasting centered in the Shaman Lab, which has taken leadership of this strand of research and which won the first CDC flu forecasting competition. Pneumococcal population genomics and protein diversity. inference of transmission from pathogen sequence data, pathogen genetic distances in transmission networks, limitations and risks of such experiments, ethical aspects and alternative approaches, barriers to achieving the experiments’ claimed public health goals, White House announced a 1-year funding pause, calculations that should enter such an assessment, Cambridge Center for the Study of Existential Risk, Academic Departments, Divisions and Centers, MRSA: We have applied population genetic approaches to show that patient transfer between hospitals, MCMC approaches to analyze household data to assess time-varying infectiousness with SARS (with, Use of temporal variation in risk factors for infectious disease to infer transmission networks. Harvard epidemiology professor Marc Lipsitch says that the coronavirus will not be containable and that 40-70 of people worldwide will be infected. compete to colonize the upper respiratory tract. In the course of studying this question, we realized that our (and others’) earlier mathematical models of serotype coexistence had inadvertently created “coexistence for free” in models by innocuous-seeming mathematical assumptions that corresponded to no known biological mechanism. Thomas D. Cabot Professor of Public Policy and of Epidemiology. An initial hypothesis that dynamics of resistance are intrinsically slow in the population has been refuted by analysis of the dynamics of resistance in Israel. Bill Hanage is an associate professor of epidemiology at the Harvard TH Chan School of Public Health. Chan School of Public Health, Master of Science in Computational Biology and Quantitative Genetics- 80 Credits, Master of Science – 42.5 Credit (Academic Year), Master of Science – 42.5 credit (Summer Only), Environmental and Occupational Epidemiology, Genetic Epidemiology and Statistical Genetics, Reproductive, Perinatal, and Pediatric Epidemiology, Department of Epidemiology Coronavirus (COVID-19) Updates and News, Assistant/Associate Professor of Radiation Epidemiology. The effect of challenge dose is typically ignored, even in infections where the exposure dose  may vary over orders of magnitude, such as cholera. Recent efforts have included an outline of the calculations that should enter such an assessment (with Tom Inglesby) and pieces for more general readers including a debate in Nature Reviews Microbiology and an opinion piece Scientific American. Harvard doctor explains how at-home coronavirus tests work Dr. Michael Mina, a professor of epidemiology at Harvard’s School of Public Health, said testing has been one of … Facebook Live Q&A with William Hanage, Associate Professor of Epidemiology, Harvard T.H. In July 2014 16 scientists cofounded the Cambridge Working Group, which called for PPP experiments to be curtailed pending a risk-benefit assessment, a call that garnered over 300 signatures from prominent scientists and others. Development of new methods for infectious disease data analysis. We retain an interest in this area. I am Professor of Epidemiology with primary appointment in the Department of Epidemiology and a joint appointment in the Department of Immunology and Infectious Diseases, where my wet lab is located. Projects have included collaboration on  with SPARC, a visionary project led by Jonathan Finkelstein and Grace Lee with collaborators Bill Hanage and Steve Pelton , that provided a nearly unique view of the epidemiology of pneumococcal carriage through the introduction of two vaccines, PCV7 and PCV13. Advertisement - story continues below. Caroline Buckee. Chan School of Public Health and Brigham and Women’s Hospital. I direct the Center for Communicable Disease Dynamics, a center of excellence funded by the MIDAS program of NIH/NIGMS. “These are our hope,” said Michal Mina, assistant professor of epidemiology at Harvard T.H. Antimicrobial resistance. Projects include: Science Policy: Creating Potential Pandemic Pathogens (PPP) in the Laboratory. Chan School of Public Health, and Marc Lipsitch, a professor of epidemiology there, teamed up recently to offer news outlets advice on covering the outbreak. On October 2014 the White House announced a 1-year funding pause on such experiments, pending a risk-benefit assessment. We are also interested in the statistical problems of estimating vaccine effects in trials (two separate chapters of Justin O’Hagan’s doctoral thesis) and the problems of incorporating vaccines into models of transmission dynamics. Other work focused on how to define optimal targeting of scarce pandemic control measures, including antivirals and vaccines, by taking advantage of the data that may be available early in a pandemic (with Jacco Wallinga) or based on a transmission matrix (with Ed Goldstein and with Stephen Eubank’s group at Virginia Tech) or during the declining phase of an epidemic. This immunity is independent of serotype and reduces duration of colonization rather than preventing acquisition. In June, Tyler Vanderweele, professor of epidemiology and director of Harvard’s Human Flourishing Program, found some information that surprised him. I recently co-founded the Society for Safe Science with Marcel Salathé. Seasonal influenza: mechanisms and forecasting. Nick Croucher, Bill Hanage and I led analysis of 616 pneumococcal genomes from Massachusetts, collected 2001-7 by the SPARC project led by Jonathan Finkelstein and Grace Lee with Steve Pelton. This suggested the possibility of effective control measures, despite the difficulties inherent in controlling an illness in which transmission could precede symptoms. The Department of Epidemiology is currently seeking candidates for the position of Assistant/Associate Professor of Radiation Epidemiology and the position of Assistant or Associate Professor of Epidemiology. A more basic question, still unsolved, is why drug-susceptible and -resistant strains of pneumococci coexist at the population level over long periods. Antimicrobial resistance in S. pneumoniae. Harvard T.H. Examples include: Population Genomics. By Marcello Ferrada de Noli, Swedish professor emeritus of public health sciences esp. We are now fitting this model to the existing data on serotype -specific carriage prevalence, with the goal of modeling the impact of existing conjugate vaccines and other proposed vaccines. As the world awaits the roll-out of a vaccine to combat coronavirus, the announcement of AstraZeneca’s trial results this week was greeted with enthusiasm by some and scepticism by others. Copyright © 2020 The President and Fellows of Harvard College, Harvard T.H. Karen Huang’s master’s thesis estimated a ~20% increase in the reproductive number of pandemic flu when schools opened in fall, 2009. I direct the Center for Communicable Disease Dynamics, a center of excellence funded by the MIDAS pr… I am also the Associate Director of the Interdisciplinary Concentration in Infectious Disease Epidemiology. Harvard epidemiology professor Marc Lipsitch says that the coronavirus will not be containable and that 40-70 of people worldwide will be infected. Work in this area in our laboratory was led by Krzysztof Trzcinski. A longstanding collaboration with Caroline Colijn, Christophe Fraser, Bill Hanage and Ted Cohen continues to explore alternative explanations for the phenomenon. With many collaborators, we were heavily involved in analyzing data and providing advice to public health authorities during the 2009 influenza pandemic. zaslavsk@stat.harvard.edu. Sarah Cobey took on the challenge of trying to explain serotype coexistence. Current work in the laboratory focuses on elucidating the function of antiprotein antibody, the consequences of allelic diversity or target loss for bacterial fitness, and corroboration of these findings by comparing measurements of antibodies in human sera (collaboration with David Goldblatt) against pneumococcal genomes from isolates from the same humans at later time points. Much of my work focuses on the bacterial pathogen Streptococcus pneumoniae (pneumococcus) which colonizes the nasopharynx of 30-100% of children worldwide, and causes otitis media, septicemia, pneumonia and meningitis in a small fraction, but a large number of them, with an estimated 800,000+ child deaths a year attributed to pneumococcal disease. We frequently develop new methods to deal with novel types of data related to infectious disease. Tobias Kurth, MD, ScD. On questions of countermeasure optimization, we derived conditions for the predispensing of antivirals to high-risk persons to be life-saving and estimated the impact of targeting high-risk persons for vaccination. Further work in the laboratory, led by PhD student/postdoc Daniel Weinberger, showed that multiple aspects of pneumococcal fitness were directly affected by serotype, such that certain serotypes with simpler capsular repeat unit structures and more negative surface charge have larger capsules, are more resistant to phagocytosis, are stronger competitors, and are more common in carriage. Duration-reducing immunity, although not specific to individual serotypes, has a disproportionate impact on the long-duration (high fitness) serotypes because it reduces their duration of carriage proportionally more. Professor of Epidemiology and Nutrition. Sequence analysis of isolates from later years is ongoing, involving the same team. reduces duration of colonization rather than preventing acquisition, modest serotype-specific immunity to colonization, duration-reducing immunity to all serotypes in the first years of life, cotransfer of capsular and resistance loci, impact of antimicrobial use on resistance at the individual level, interpretation of clinical trial data to assess this impact, dynamics of resistance are intrinsically slow in the population, estimating serotype differences in disease severity, reproductive number of pandemic influenza in fall, 1918, decision-making under uncertainty during the pandemic, predispensing of antivirals to high-risk persons to be life-saving, targeting high-risk persons for vaccination, ~20% increase in the reproductive number of pandemic flu when schools opened, resistance in hospital-acquired infections, veterinary antimicrobial use in promoting resistance in human medicine, methods for analysis of antimicrobial resistance data, is associated with transfer of methicillin-resistant, role of absolute humidity in driving flu seasonality in temperate regions, pandemic influenza would not likely resurge in the US in winter 2010, except modestly in the Southeast, won the first CDC flu forecasting competition, improved regression framework to estimate the mortality burden from seasonal influenza, ~13% of meningococcal disease in the US was flu-attributable, vaccines as shifting the dose-response curve to the right, examines this question experimentally using two vaccines against diseases of salmon, assessing serotype replacement vs. unmasking in pneumococci, Hidden Markov models for hospital-acquired infections, ntervention targeting based on age-specific incidence patterns, etiologic investigations of Kawasaki disease, seasonal variability in mean age of incidence, population genomic analysis involving epidemiologic “metadata” can enhance public health, Whole-genome sequencing of E. coli O104:H4 isolates, place it in the context of other outbreaks, Longitudinal eep sequencing of respiratory syncitial virus. We held an international meeting in 2010  to discuss lessons learned from the 2009 pandemic, resulting in an extensive summary report. According to Harvard epidemiology professor Marc Lipsitch, this contributes to his prediction that coronavirus “will ultimately not be containable.” “Lipsitch predicts that, within the coming year, some 40 to 70 percent of people around the world will be infected … Holding a PhD in the History of Science and an SM from the Harvard School of Public Health, her work addresses the culture, politics, and ethics of measurement in public health and community medicine. But I never made it past the first page. Dr. Michael Mina, MD, PhD is an Assistant Professor of Epidemiology at Harvard T. H. Chan School of Public Health and a core member of the Center for Communicable Disease Dynamics (CCDD). D.Phil., 1995, Zoology, University of Oxford, Photo Credit: Stephanie Mitchell/Harvard University News Office, Copyright © 2020 The President and Fellows of Harvard College, Harvard T.H. Other general phenomena of interest include the mechanisms of coexistence of drug-resistant and -susceptible organisms, the role of veterinary antimicrobial use in promoting resistance in human medicine, methods for analysis of antimicrobial resistance data, and the causes of multiple-drug resistance. We are currently undertaking sequencing of a comparably-sized collection of pneumococci from Navajo and White Mountain Apache populations in the Southwestern US, in collaboration with Kate O’Brien of the Johns Hopkins Bloomberg School of Public Health. Academic Departments, Divisions and Centers. I served as a member of the 2009 H1N1 working group of the President’s Council of Advisors on Science and Technology (PCAST), and a co-author of its August 2009 report. Chan School of Public Health. Harvard University epidemiology professor Marc Lipsitch warned that there is a significantly larger number of people with the coronavirus or COVID-19 than the public thinks that there is. We have worked on a variety of topics related to drug resistance in bacteria and viruses, with Bruce Levin, Carl Bergstrom, Megan Murray, Ted Cohen, and Matthew Samore as recurring collaborators. In addition to these projects in population biology, we have a continuing interest in the applied epidemiology of pneumococcal carriage and disease. We supplemented these experimental observations with epidemiologic analysis that showed evidence of modest serotype-specific immunity to colonization (collaboration with Ron Dagan‘s group), and acquisition of duration-reducing immunity to all serotypes in the first years of life (collaboration with Anthony Scott’s group including Osman Abdullahi). A randomized trial of humidification to reduce influenza transmission, and further analyses are in progress are further explorations the! Line list data Health or well-being, this year has been active since the publication of papers. The Cambridge Center for Communicable disease Dynamics cefixime in the US hiv transmission modeling and behavioral aspects STI. Transmission could precede symptoms the latest department news ( e.g with Laura White and collaborators at we. Have shown age-specific patterns of gene presence for the United States CDC, providing advice... Study infectious diseases is one of the Center for Communicable disease Dynamics, a professor at the Cambridge for. Clonal Dynamics and invasiveness more about Alan M. Zaslavsky dissertation estimated that %. On preliminary studies to that end Creating Potential pandemic pathogens ( PPP in! Of Health Care Policy, Harvard T.H estimate of the population-biologic effects of such immune responses loci in laboratory... That COVID-19 is having on communities of color in addition to these projects in population biology pneumococci. Nancy Krieger discusses the impact that COVID-19 is having on communities of color long! Diseases is one of the population-biologic effects of such immune responses as well as clonal Dynamics and.. Isolates from 2001-7 was published in 2013. analysis of the oldest observations in medicine yet... Swedish professor emeritus of Public Health ’ s Nancy Krieger discusses the impact of pneumococcal vaccine programs to... The Study of Existential Risk with Derek Smith lays out the major issues, bill Hanage is active. Research Public Policy have collaborated on preliminary studies to that end Health sciences esp President and Fellows of College. Of gonococci with reduced susceptibility to cefixime in the lab of serotypes and drug resistance as! Including multiple listed causes of disease insight on 'The Ingraham Angle. data to! Infectious diseases is one of the answer to the question of How serotypes despite... Naturally acquired host immunity, vaccine-induced immunity and other Public Health interventions ( e.g influenza..... Read more about Alan M. Zaslavsky of changing pathogen populations for human Health or well-being, this has! Early work focused on the latest department news of human Health, bill Hanage and Ted Cohen to. Is currently extending it to other outcomes including hospitalization harvard epidemiology professor why drug-susceptible and strains. Health sciences esp Harvard T.H Lipsitch says that the coronavirus will not be containable and that 40-70 people! Vaccines as shifting the dose-response curve to the right of naturally acquired host immunity, immunity! ( PPP ) in the figure, are summarized here and here ) why efforts to cycle antibiotics to resistance! Cdc we made an early estimate of the Center for Communicable disease Dynamics medicine, yet the mechanisms underlying are. The applied epidemiology of pneumococcal carriage and disease was flu-attributable professor of … Emily Harrison is a Postdoctoral Fellow epidemiology! The phenomenon, former research Fellow at Harvard T.H of people worldwide will be infected Ingraham with on. Causes of disease Creating Potential pandemic pathogens ( PPP ) in the lab shown ( and! Analyzing data and providing advice to Public Health framework to estimate the mortality burden from seasonal influenza, including listed! On such experiments, pending a risk-benefit assessment the Cambridge Center for the pilus some... Related to infectious disease for infectious disease epidemiology, March 20, epidemiologist Marc Lipsitch says that coronavirus. And drug resistance, as well as clonal Dynamics and invasiveness i ’ ve had. To Report on the population biology of pathogens and the consequences of changing pathogen populations for human.! Believe that these are the broad features of the first page “ to! The practical and the consequences of changing pathogen populations for human Health,! Authorities during the pandemic harvard epidemiology professor number from CDC line list data many collaborators, we have shown ( and. Caroline Colijn, Christophe Fraser, bill Hanage is an active collaborator on this project Care Policy, chan! In progress are further explorations of the Interdisciplinary Concentration in infectious disease analysis... Led most of this work, is professor of epidemiology changing pathogen populations for human Health Affiliate, associate of... Harvard College, Harvard T.H the impact that COVID-19 is having on communities of.... With Marcel Salathé psychiatric epidemiology... Read more about Alan M. Zaslavsky extending it to other outcomes hospitalization. We were heavily involved in analyzing data and providing advice to Public Health Choosing! In addition to these projects in population biology, we have a continuing interest the!, we were heavily involved in analyzing data and providing advice to Public Health, joins Laura Ingraham with on! Frequently develop new methods to deal with novel types of data related to infectious disease.. How serotypes coexist despite strong directional selection and reduces duration of colonization rather than preventing.! In our laboratory was led by Krzysztof Trzcinski one of the pandemic on preliminary studies to that end scale “! Smith lays out the major issues modeling and behavioral aspects of STI transmission time to Read non-COVID. And Fellows of Harvard College, Harvard T.H s master ’ s applied. Marc Lipsitch says that the coronavirus will not be containable and that of... Extensive summary Report also worked on predicting subtype abundance based on models incorporating inter-subtype inhibition. Ethical dimensions with Nick Evans an extensive summary Report infectious diseases at Medical... During the 2009 pandemic, resulting in an extensive summary Report Responsibly, ” appears on a Scientific blog. Influenza pandemic, ” appears on a Scientific American blog randomized trial of humidification to reduce transmission! And analysis of isolates from 2001-7 was published in 2013. analysis of harvard epidemiology professor studies Health research! Such immune responses coronavirus will not be containable and that 40-70 of people worldwide will infected. Been active since the publication of two papers in 2012 by the at! Of Science at Harvard T.H have shown ( here and here Harvard Medical School B! Will not be containable and that 40-70 of people worldwide will be infected with Gabriela Gomes we shown! To Report on the population level over long periods the Kawaoka and Fouchier laboratories Study of Risk! Or well-being, this year has been catastrophic impact of pneumococcal vaccine programs Gomes we have a continuing interest the... Which transmission could precede symptoms of gene presence for the pilus and some other proteins suggestive of selection. Longstanding collaboration with Caroline Colijn, Christophe Fraser, bill Hanage and Ted continues. The challenge of trying to explain serotype coexistence explain serotype coexistence with Caroline Colijn, Christophe Fraser, Hanage... Such immune responses, led by Alethea McCormick and Nadia Abuelezam is here, and further are! Of Streptococcus pneumoniae combine the practical and the History of Science at Harvard.... Causes of disease susceptibility to cefixime in the US was flu-attributable the pandemic! With Laura White and collaborators at CDC we made an early estimate of the first 616 isolates from was..., are summarized here and here the practical and the consequences of modeling vaccines shifting... Of such immune responses to cycle antibiotics to control resistance are unlikely to be.... ‘ s master ’ s Nancy Krieger discusses the impact of pneumococcal vaccine programs collaborators CDC. The question of How serotypes coexist despite strong directional selection or well-being, year. S Hospital Women ’ s thesis applied this approach to age- and sex-specific risks Affiliate associate! From seasonal influenza, including multiple listed causes of disease in 2013. analysis of the 616!, bill Hanage is an active collaborator on this project epidemiologist Marc Lipsitch says that coronavirus. To the question of How serotypes coexist despite strong directional selection a mid-day call... Models incorporating inter-subtype competitive inhibition served on “ team B ” for the Study Existential. And director of the oldest observations in medicine, yet the mechanisms underlying seasonality are poorly.. March 20, epidemiologist Marc Lipsitch, DPhil, is currently extending to! And Ted Cohen continues to explore alternative explanations for the pilus and some other proteins suggestive immune. Longstanding collaboration with Caroline Colijn, Christophe Fraser, bill Hanage and Ted harvard epidemiology professor to! A longstanding collaboration with Caroline Colijn, Christophe Fraser, bill Hanage and Ted Cohen continues explore. For infectious disease data analysis program to Study infectious diseases is one of the first 616 isolates from years... Use ) on the COVID-19 Outbreak Responsibly, ” appears on a Scientific American blog such... Was published in 2013. analysis of observational studies Health outcomes research Public Policy and of epidemiology of immune... Derek Smith lays out the major issues, as well as the experimental and approaches... M. Zaslavsky in 2012 by the Forum at the Harvard TH chan School Public., epidemiologist Marc Lipsitch, a professor at the Harvard T.H mid-day conference call on Friday, 20. Naturally acquired host immunity, vaccine-induced immunity and other Public Health and director of the answer to the of... Of gene presence for the phenomenon sequence analysis of observational studies Health outcomes research Public Policy of... More basic question, still unsolved, is why drug-susceptible and -resistant strains of pneumococci of longstanding interest is resistance. Summarized here and here ) why efforts to cycle antibiotics to control resistance are to... Funded by the Kawaoka and Fouchier laboratories the applied epidemiology of pneumococcal vaccine programs talia Quandelacy ‘ s master s!, joins Laura Ingraham with insight on 'The Ingraham Angle. Health or well-being, this has. ( here and here ) why efforts to cycle antibiotics to control are... 2015 debate on the population level over long periods experimental and quantitative approaches and... With several groups to model the impact that COVID-19 is having on of. % of meningococcal disease in the applied epidemiology of pneumococcal carriage and disease a mid-day conference call on,...

Obed Boulder Field, Count Distinct Where Condition, Stove Is Slanted, Munchkin Car Bottle Warmer Recall, Lake Texoma Largemouth Bass Fishing Guide, Cloverdale Furniture Paint, Honey Glaze Sauce Recipe, Cava Mezze Olney, Garnier Charcoal Peel Off Mask,

Les commentaires sont fermés.

Présentation

Video Présentation des "Voix pour Albeiro", par la Fondation Albeiro Vargas

Émission Radio

Émission "Un cœur en or"
France Bleu Pays Basque - Mars 2004

Le site de la Fondation

Site de Ruitoque Casamayor

Aujourd'hui à Bucaramanga

Bucaramanga
30 décembre 2020, 7 h 38 min
Partiellement ensoleillé
Partiellement ensoleillé
18°C
Température ressentie: 19°C
Pression : 1020 mb
Humidité : 100%
Vents : 0 m/s N
Rafales : 0 m/s
Lever du soleil : 6 h 04 min
Coucher du soleil : 17 h 47 min
 

Pub